Eizellspende, oder manchmal auch als Spenderei IVF-Behandlung bezeichnet, bezieht sich auf die IVF-Behandlung mit Spendereiern. Diese Option ist für Frauen geeignet, die aus verschiedenen Gründen nicht mit eigenen Eizellen schwanger werden können.
Wer braucht eine Behandlung zur Eizellspende?
Frauen, die nicht in der Lage sind, mit ihren eigenen Eizellen schwanger zu werden, können wie folgt kategorisiert werden:
1- Frauen mit vorzeitigem Eierstockversagen und/oder vorzeitiger Menopause. Auch wenn vorzeitiges Eierstockversagen und vorzeitige Menopause manchmal austauschbar eingesetzt werden, sind die beiden Konzepte nicht genau gleich. Vorzeitiges Versagen der Eierstöcke bezieht sich auf Eierstöcke, die ihre normale Funktion vor dem Alter von 40 Jahren verlieren. Frauen mit vorzeitigem Eierstockversagen können noch Perioden haben, auch wenn sie nicht regelmäßig sind und sogar schwanger werden können, obwohl die Chancen auf eine Schwangerschaft sehr gering sind. Unter vorzeitiger Menopause versteht man den vorzeitigen Eintritt in die Menopause ohne weitere Menstruation Zyklus
2- Frauen, die einer Chemotherapie oder Strahlentherapie unterzogen wurden. Dies kann auf eine Krebsbehandlung oder eine andere medizinische Behandlung zurückzuführen sein. In der Regel verlieren Frauen, die einer Chemotherapie oder Strahlentherapie unterzogen wurden, ihre Eierstockreserven.
3- Frauen, deren Eierstöcke beschädigt oder entfernt wurden. Einige Krankheiten erfordern die Entfernung eines oder beider Eierstöcke. Wenn die Eierstöcke während einer Operation beschädigt oder vollständig entfernt wurden, hat der Patient keinen Eisprung mehr, d.h. er hat keine lebensfähigen Eier mehr für die Schwangerschaft.
4- Frauen mit genetischen Erbkrankheiten, die dem Risiko ausgesetzt sind, genetische Krankheiten an die neue Generation weiterzugeben, können sich für eine Eizellenspende entscheiden, um den genetischen Zustand in der Familie zu vermeiden.
5- Frauen, die natürlich in die Menopause eingetreten sind und aufgrund des hohen Alters nicht mehr mit eigenen Eiern schwanger werden können.
At North Cyprus IVF Center, Egg donor IVF program requires a number of steps before proceeding with treatment. This is to make sure that this treatment option is right for you and also to make sure that you are fit for pregnancy and that there are no problems that might interfere with a successful pregnancy. The steps involved in treatment can be listed as follows:
Steps in Egg Donor IVF Treatment:
1- Making the initial contact: At this point, we will make first contact and based on information provided by you, we will make an initial assessment. The more details you provide, the more comprehensive our responses and recommendations can be. For this end, we ask that you provide us with as much detail as possible regarding your history of infertility, previous testing and/or previous history of infertility and IVF treatments. You can contact us using the contact form on our website, or simply fill out the “Patient application form” with as much detail as possible so that we can provide you with a more comprehensive response.
2- Initial Assessment and Preliminary Testing: At this point, based on your history of infertility and previous testing and treatment history, we will make an assessment of your treatment needs and requirements. Additional tests and diagnoses may be required depending on your specific case. Generally speaking, we will first want to make sure that you are fit for pregnancy and that there are no problems thatc an interfere with a successful pregnancy. These will necessitate the following tests:
– If you have regular menstrual cycles, then we will need a base line ultrasound scan (sonogram) on day 2 or day 3 of your menstrual period. If you do not have regular menstrual cycles, the scan can be done at any time. The purpose of the scan is to observe the ovaries and the uterus and make sure everything looks normal and as expected.
– If you have a history of failed IVF cycles and a case of unexplained infertility, then we will also ask that both you and your husband have a genetic karyotype analysis done to rule out any chromosomal abnormalities. A karyotype analysis does not cost too much and it can provide us with very important insights when explaining unexplained infertility.
– If you have a history of recurrent miscarriages or repeated IVF failures, then we will need you to undergo thrombophilia testing to see of there are any thrombophilia (blood clotting problems).
– It’s not necessary but it’s a good idea to have a hysterosalpingography (HSG) filming done before an IVF treatment. If you have had at least one failed treatment before, then HSG is a must.
– We will need your partner to have his semen analysis done to measure parameters such as count, volume, motility, morphology, pH and round cell count. We will need to make sure that his semen sample is suitable for ICSI treatment.
– Both you and your partner will need to undergo infectious disease screening.
3- Treatment Planning: Based on test results and all the information we have gathered up until this point, we will be able to formulate a treatment plan and a calendar to be followed. The initial preparations, including medication use and follow up scans, can be done locally in your own country with your own gynecologist or scan place, or if you do not have your own doctor, we can recommend a name or two in your area for the tests. Based on your treatment calendar, we will also be able to provide you with a prescription so that you can obtain your medication locally.
4- Actual Treatment: This is when you will need to travel to North Cyprus. Usually, if you are able to have your scans done locally, the length of stay in North Cyprus will be around 6 days. You will need to arrive here in time for your egg donor’s oocyte pick-up (OPU) procedure so that your partner can provide his fresh sample for a fresh round of ICSI with fresh eggs in order to give you the highest chance of success possible. Ideally, embryos are cultivated in an incubator for 3 to 5 days until they reach a suitable level of growth so that they can be transferred into the uterus. Depending on the number and quality of your embryos on day 1 check, you will have a chance to choose the stage at which the embryos are transferred. We are happy to offer day 5 blastocyst transfer to all our patients free of charge, however, it should be known that even though blastocyst embryos have higher quality grading and have better pregnancy rates, some of the embryos will not make it into day 5 blastocyst stage although they would have generated pregnancy should they have been transferred on day 3. So, there is a trade-off between the number of your embryos and the quality grading when it comes to deciding when to have the embryo transfer done. Our recommendation usually is to proceed with day 3 transfer unless there is a specific reason why your doctor might think day 5 embryo transfer will be a better option. Also, if you are having PGD screening done on your embryos, that will also necessitate a day 5 blastocyst transfer as testing and screening will take time.
Another important part of the egg donation program at North Cyprus IVF Centre is the choice of your egg donor. Even though North Cyprus laws require complete donor anonymity, we are still able to provide you with certain information regarding our donors. As a general rule, our donors should comply with the following standards:
– Must be aged between 19-29
– Must have her body mass index (BMI) in the normal range
– Must be mentally stable and must pass her psychological evaluation
– Must go through infectious disease screening
– Must go through hormone testing and fertility assessment
– If donor is from a certain geographic region with any genetic predispositions, she must go through additional testing.
Optionally, egg donors can undergo genetic karyotype analysis and additional screening per your request, but these will have associated additional costs.
Our donors are predominantly consisted of international university students studying at universities in North Cyprus. Most donors are aged between 19-25 and we prefer that donors we use in our egg donation program have a successful donation history. Each egg donor is allowed to donate up to 5 times in her lifetime and donors whose previous donations have created a positive outcome are called back in the upcoming months to donate again. That way, we can make sure that the eggs that we provide in your IVF program are pregnancy proven and that we can offer you a high chance of success with your treatment.